Plants are well known to possess various medicinal properties. The present study is conducted to evaluate the phytochemical profile and antibacterial activity of ripe fruits of Cassia fistula Linn. Studies on the antibacterial activity of 90% ethanol extract of Cassia fistula ripe fruits and it’s ethyl acetate and n-butanol fractions were conducted using disc diffusion method. The microorganisms used were Bacillus subtilis, Staphylococcus aureus, Escherichia coli, Salmonella typhi, Pseudomonas aeruginosa and Klebsiella pneumoniae. The antibacterial activity was observed against all microorganisms. The minimum inhibitory concentration of different extracts ranged between 5mg/ml and 0.078mg/ml depending upon the microorganism however in some cases, the MIC was above 5mg/ml. Presence of phytochemicals such as flavonoids, saponins, terpenoids and tannins was observed in different extracts. Cassia fistula was observed to have antibacterial activity and can be used for medicinal purpose.
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